Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192.

J Bacteriol, 2010/12;192(24):6492-3.

Angelov A[1], Liebl S, Ballschmiter M, Bömeke M, Lehmann R, Liesegang H, Daniel R, Liebl W

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PMID: 20935097DOI: 10.1128/JB.01023-10

Impact factor: 3.476

Abstract
Spirochaeta thermophila is a thermophilic, free-living anaerobe that is able to degrade various α- and β-linked sugar polymers, including cellulose. We report here the complete genome sequence of S. thermophila DSM 6192, which is the first genome sequence of a thermophilic, free-living member of the Spirochaetes phylum. The genome data reveal a high density of genes encoding enzymes from more than 30 glycoside hydrolase families, a noncellulosomal enzyme system for (hemi)cellulose degradation, and indicate the presence of a novel carbohydrate-binding module.
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