Transmission of hemagglutinin D222G mutant strain of pandemic (H1N1) 2009 virus.
Emerg Infect Dis, 2010/5;16(5):863-5.
Puzelli S[1], Facchini M, Spagnolo D, De Marco MA, Calzoletti L, Zanetti A, Fumagalli R, Tanzi ML, Cassone A, Rezza G, Donatelli I, Surveillance Group for Pandemic A H1N1 2009 Influenza Virus in Italy
Affiliations
PMID: 20409386DOI: 10.3201/eid1605.091815
Impact factor: 16.126
Abstract
A pandemic (H1N1) 2009 virus strain carrying the D222G mutation was identified in a severely ill man and was transmitted to a household contact. Only mild illness developed in the contact, despite his obesity and diabetes. The isolated virus reacted fully with an antiserum against the pandemic vaccine strain.
MeSH terms
Adult; Amino Acid Substitution; Disease Outbreaks; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Mutation, Missense; Phylogeny; RNA, Viral; Retrospective Studies; Sequence Analysis, RNA; Severity of Illness Index
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