Physiological versatility of the extremely thermoacidophilic archaeon Metallosphaera sedula supported by transcriptomic analysis of heterotrophic, autotrophic, and mixotrophic growth.
Appl Environ Microbiol, 2010/2;76(3):931-5.
Auernik KS[1], Kelly RM
Affiliations
PMID: 20008169DOI: 10.1128/AEM.01336-09
Impact factor: 5.005
Abstract
Comparative transcriptomic analysis of autotrophic, heterotrophic, and mixotrophic growth of the archaeon Metallosphaera sedula (70 degrees C, pH 2.0) revealed candidates for yet-to-be-confirmed components of the 3-hydroxypropionate/4-hydroxybutyrate pathway and implicated a membrane-bound hydrogenase (Msed_0944-Msed_0946) for growth on H(2). Routes for generation of ATP and reducing equivalents were also identified.
MeSH terms
Aerobiosis; Archaeal Proteins; Autotrophic Processes; Carbon Dioxide; Carbon Isotopes; Gene Expression Profiling; Gene Expression Regulation, Archaeal; Heterotrophic Processes; Hot Temperature; Hydroxybutyrates; Oligonucleotide Array Sequence Analysis; Substrate Specificity; Sulfolobaceae; Temperature
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