Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.
Antimicrob Agents Chemother, 2008/11;52(11):4198-202.
Zong Z[1], Partridge SR, Thomas L, Iredell JR
Affiliations
PMID: 18725449DOI: 10.1128/AAC.00107-08
Impact factor: 5.938
Abstract
bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids.
MeSH terms
Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; New South Wales; Plasmids; beta-Lactam Resistance; beta-Lactamases
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