Improvement of Lactobacillus plantarum aerobic growth as directed by comprehensive transcriptome analysis.

Appl Environ Microbiol, 2008/8;74(15):4776-8.

Stevens MJ[1], Wiersma A, de Vos WM, Kuipers OP, Smid EJ, Molenaar D, Kleerebezem M

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PMID: 18539801DOI: 10.1128/AEM.00136-08

Impact factor: 5.005

Abstract
An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that resumption of growth after stagnation correlated with activation of CO(2)-producing pathways, suggesting that a limiting CO(2) concentration induced the stagnation. Analogously, increasing the CO(2) gas partial pressure during aerobic fermentation prevented the temporal growth stagnation.
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