Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T.
PLoS Genet, 2008/5/30;4(5):e1000087.
Weiner RM[1], Taylor LE 2nd, Henrissat B, Hauser L, Land M, Coutinho PM, Rancurel C, Saunders EH, Longmire AG, Zhang H, Bayer EA, Gilbert HJ, Larimer F, Zhulin IB, Ekborg NA, Lamed R, Richardson PM, Borovok I, Hutcheson S
Affiliations
PMID: 18516288DOI: 10.1371/journal.pgen.1000087
Impact factor: 6.02
Abstract
The marine bacterium Saccharophagus degradans strain 2-40 (Sde 2-40) is emerging as a vanguard of a recently discovered group of marine and estuarine bacteria that recycles complex polysaccharides. We report its complete genome sequence, analysis of which identifies an unusually large number of enzymes that degrade >10 complex polysaccharides. Not only is this an extraordinary range of catabolic capability, many of the enzymes exhibit unusual architecture including novel combinations of catalytic and substrate-binding modules. We hypothesize that many of these features are adaptations that facilitate depolymerization of complex polysaccharides in the marine environment. This is the first sequenced genome of a marine bacterium that can degrade plant cell walls, an important component of the carbon cycle that is not well-characterized in the marine environment.
MeSH terms
Alteromonadaceae; Bacterial Proteins; Base Sequence; Chromosome Mapping; Genome, Bacterial; Glycoside Hydrolases; Molecular Sequence Data; Polysaccharides; Protein Transport; Seawater; Sequence Analysis, DNA; Signal Transduction; Substrate Specificity
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