First detection of a carbapenem-hydrolyzing metalloenzyme in two enterobacteriaceae isolates in Spain.
Antimicrob Agents Chemother, 2005/8;49(8):3492-4.
Tórtola MT[1], Lavilla S, Miró E, González JJ, Larrosa N, Sabaté M, Navarro F, Prats G
Affiliations
PMID: 16048967
Impact factor: 5.938
Abstract
Two strains of Enterobacteriaceae, Escherichia coli and Klebsiella pneumoniae, producing VIM-1 were isolated for the first time in Spain. In both strains, bla(VIM-1) was found to be carried on a gene cassette inserted into a class 1 integron. The bla(VIM-1)-containing integron was located on a transferable plasmid.
MeSH terms
Anti-Bacterial Agents; Carbapenems; Conjugation, Genetic; Enterobacteriaceae Infections; Escherichia coli; Humans; Integrons; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Spain; beta-Lactam Resistance; beta-Lactamases
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