Survey of Enterobacteriaceae producing extended-spectrum beta-lactamases in a Slovak hospital: dominance of SHV-2a and characterization of TEM-132.
Antimicrob Agents Chemother, 2005/7;49(7):3066-9.
Zarnayová M[1], Siebor E, Péchinot A, Duez JM, Bujdáková H, Labia R, Neuwirth C
Affiliations
PMID: 15980402
Impact factor: 5.938
Abstract
Eighty-five extended-spectrum beta-lactamase-producing Enterobacteriaceae from a Slovak hospital have been studied. SHV-2a was predominant, but other variants have been detected, namely, SHV-5, SHV-12, TEM-12, TEM-15, and TEM-132, which differed from TEM-1 by amino acid substitutions R164H, E240K, and I173V and had kinetic properties similar to those of TEM-28.
MeSH terms
Anti-Bacterial Agents; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA; Slovakia; beta-Lactam Resistance; beta-Lactamases; beta-Lactams
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