Dictyosphaeric acids A and B: new decalactones from an undescribed Penicillium sp. obtained from the alga Dictyosphaeria versluyii.

J Nat Prod, 2004/8;67(8):1396-9.

Bugni TS[1], Janso JE, Williamson RT, Feng X, Bernan VS, Greenstein M, Carter GT, Maiese WM, Ireland CM

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PMID: 15332862

Impact factor: 4.803

Abstract
Fungal isolate F01V25 was obtained from the alga Dictyosphaeria versluyii collected near Dravuni, Fiji, in 2001 and represented a previously undescribed Penicillium sp. Fermentation of isolate F01V25 resulted in the production of two new polyketides, dictyosphaeric acids A and B, along with the known anthraquinone carviolin. The relative stereochemistry of dictyosphaeric acids A and B was determined using the J-based configuration analysis method in conjunction with ROE and NOE correlations.
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