Novel tetracycline resistance gene, tet(32), in the Clostridium-related human colonic anaerobe K10 and its transmission in vitro to the rumen anaerobe Butyrivibrio fibrisolvens.
Antimicrob Agents Chemother, 2001/11;45(11):3246-9.
Melville CM[1], Scott KP, Mercer DK, Flint HJ
Affiliations
PMID: 11600392
Impact factor: 5.938
Abstract
A novel tetracycline resistance gene, designated tet(32), which confers a high level of tetracycline resistance, was identified in the Clostridium-related human colonic anaerobe K10, which also carries tet(W). tet(32) was transmissible in vitro to the rumen anaerobe Butyrivibrio fibrisolvens 2221(R). The predicted gene product of tet(32) has 76% amino acid identity with Tet(O). PCR amplification indicated that tet(32) is widely distributed in the ovine rumen and in porcine feces.
MeSH terms
Anaerobiosis; Animals; Cattle; Clostridium; Colon; DNA, Bacterial; Humans; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Rumen; Tetracycline Resistance; Vibrionaceae
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