Paramecium genome survey: a pilot project.
Trends Genet, 2001/6;17(6):306-8.
Dessen P[1], Zagulski M, Gromadka R, Plattner H, Kissmehl R, Meyer E, Bétermier M, Schultz JE, Linder JU, Pearlman RE, Kung C, Forney J, Satir BH, Van Houten JL, Keller AM, Froissard M, Sperling L, Cohen J
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PMID: 11377780
Impact factor: 11.821
Abstract
A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.
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