Mael maelstrom spermatogenic transposon silencer [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 98558)
Source: NCBI Gene (ID 98558)
Symbol: Mael
Full name: maelstrom spermatogenic transposon silencer
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4933405K18Rik
Summary: Predicted to enable sequence-specific DNA binding activity. Involved in DNA methylation involved in gamete generation; gene silencing by RNA; and piRNA metabolic process. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; male gamete generation; and negative regulation of macromolecule metabolic process. Located in several cellular components, including chromosome; cytoplasmic ribonucleoprotein granule; and perinuclear region of cytoplasm. Is expressed in brain; early conceptus; and genitourinary system. Orthologous to human MAEL (maelstrom spermatogenic transposon silencer). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward testis adult (RPKM 282.2)
Orthologs: human
Gene size: 37360bp
Exon count: 12