RIPOR2 RHO family interacting cell polarization regulator 2 [ Homo sapiens (human) ] - Gene - Data resources

9750

RIPOR2 RHO family interacting cell polarization regulator 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9750)

Symbol: RIPOR2

Full name: RHO family interacting cell polarization regulator 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: C6orf32; DFNA21; DFNB104; DIFF40; DIFF48; FAM65B; MYONAP; PL48

Summary: This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016]

Expression: Biased expression in lymph node (RPKM 23.2), spleen (RPKM 16.0) and 11 other tissues

Orthologs: mouse

Gene size: 237885bp

Exon count: 28