Full name: CART prepropeptide

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CART

Summary: This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]

Expression: Biased expression in adrenal (RPKM 51.3), brain (RPKM 5.7) and 1 other tissue

Gene size: 1771bp

Exon count: 3