ZFYVE9 zinc finger FYVE-type containing 9 [ Homo sapiens (human) ] - Gene - Data resources

9372

ZFYVE9 zinc finger FYVE-type containing 9 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9372)

Symbol: ZFYVE9

Full name: zinc finger FYVE-type containing 9

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MADHIP; NSP; PPP1R173; SARA; SMADIP

Summary: This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Expression: Ubiquitous expression in brain (RPKM 8.0), thyroid (RPKM 7.9) and 25 other tissues

Orthologs: mouse

Gene size: 204546bp

Exon count: 21