HMGN3 high mobility group nucleosomal binding domain 3 [ Homo sapiens (human) ] - Gene - Data resources

9324

HMGN3 high mobility group nucleosomal binding domain 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9324)

Symbol: HMGN3

Full name: high mobility group nucleosomal binding domain 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PNAS-24; PNAS-25; TRIP7

Summary: The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]

Expression: Ubiquitous expression in heart (RPKM 45.8), adrenal (RPKM 40.5) and 25 other tissues

Orthologs: mouse

Gene size: 33438bp

Exon count: 7