TRIP12 thyroid hormone receptor interactor 12 [ Homo sapiens (human) ] - Gene - Data resources

9320

TRIP12 thyroid hormone receptor interactor 12 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9320)

Symbol: TRIP12

Full name: thyroid hormone receptor interactor 12

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MRD49; TRIP-12; TRIPC; ULF

Summary: The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]

Expression: Broad expression in testis (RPKM 48.5), thyroid (RPKM 17.6) and 24 other tissues

Orthologs: mouse

Gene size: 159350bp

Exon count: 45