PIGM phosphatidylinositol glycan anchor biosynthesis class M [ Homo sapiens (human) ]
Source: NCBI Gene (ID 93183)
Source: NCBI Gene (ID 93183)
Symbol: PIGM
Full name: phosphatidylinositol glycan anchor biosynthesis class M
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: GPI-MT-I
Summary: This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Orthologs: mouse
Gene size: 7038bp
Exon count: 1