NAPRT nicotinate phosphoribosyltransferase [ Homo sapiens (human) ] - Gene - Data resources

93100

NAPRT nicotinate phosphoribosyltransferase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 93100)

Symbol: NAPRT

Full name: nicotinate phosphoribosyltransferase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: NAPRT1; PP3856

Summary: Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]

Expression: Ubiquitous expression in duodenum (RPKM 19.1), small intestine (RPKM 16.7) and 25 other tissues

Orthologs: mouse

Gene size: 5457bp

Exon count: 13