MARVELD3 MARVEL domain containing 3 [ Homo sapiens (human) ] - Gene - Data resources

91862

MARVELD3 MARVEL domain containing 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 91862)

Symbol: MARVELD3

Full name: MARVEL domain containing 3

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MARVD3; MRVLDC3

Summary: Enables mitogen-activated protein kinase kinase kinase binding activity. Involved in bicellular tight junction assembly. Acts upstream of or within several processes, including negative regulation of JNK cascade; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Located in bicellular tight junction and cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in small intestine (RPKM 6.8), colon (RPKM 6.5) and 18 other tissues

Orthologs: mouse

Gene size: 15782bp

Exon count: 5