Full name: chaperonin containing TCP1 subunit 6A

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CCT-zeta; CCT-zeta-1; CCT6; Cctz; HTR3; MoDP-2; TCP-1-zeta; TCP20; TCPZ; TTCP20

Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]

Expression: Ubiquitous expression in appendix (RPKM 44.1), lymph node (RPKM 38.8) and 25 other tissues

Gene size: 12225bp

Exon count: 14