LDB2 LIM domain binding 2 [ Homo sapiens (human) ] - Gene - Data resources

9079

LDB2 LIM domain binding 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 9079)

Symbol: LDB2

Full name: LIM domain binding 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CLIM1; LDB-2; LDB1

Summary: The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Expression: Broad expression in endometrium (RPKM 25.9), fat (RPKM 24.8) and 23 other tissues

Orthologs: mouse

Gene size: 397105bp

Exon count: 17