KNSTRN kinetochore localized astrin (SPAG5) binding protein [ Homo sapiens (human) ] - Gene - Data resources

90417

KNSTRN kinetochore localized astrin (SPAG5) binding protein [ Homo sapiens (human) ]
Source: NCBI Gene (ID 90417)

Symbol: KNSTRN

Full name: kinetochore localized astrin (SPAG5) binding protein

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: C15orf23; HSD11; ROCHIS; SKAP; TRAF4AF1

Summary: Enables microtubule plus-end binding activity and protein homodimerization activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; mitotic sister chromatid segregation; and regulation of attachment of spindle microtubules to kinetochore. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and ruffle. Implicated in actinic keratosis and skin squamous cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in testis (RPKM 31.0), thyroid (RPKM 17.6) and 23 other tissues

Orthologs: mouse

Gene size: 11568bp

Exon count: 9