KALRN kalirin RhoGEF kinase [ Homo sapiens (human) ] - Gene - Data resources

8997

KALRN kalirin RhoGEF kinase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8997)

Symbol: KALRN

Full name: kalirin RhoGEF kinase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD

Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]

Expression: Broad expression in brain (RPKM 3.5), small intestine (RPKM 1.5) and 20 other tissues

Orthologs: mouse

Gene size: 692957bp

Exon count: 67