Full name: calcium voltage-gated channel subunit alpha1 G

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Ca(V)T.1; Cav3.1; NBR13; SCA42; SCA42ND

Summary: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]

Expression: Biased expression in brain (RPKM 2.7), endometrium (RPKM 1.7) and 7 other tissues

Gene size: 66760bp

Exon count: 38