CCKBR cholecystokinin B receptor [ Homo sapiens (human) ]
Source: NCBI Gene (ID 887)
Symbol: CCKBR
Full name: cholecystokinin B receptor
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CCK-B; CCK2R; GASR
Summary: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]
Expression: Biased expression in stomach (RPKM 4.6), brain (RPKM 2.9) and 2 other tissues
Orthologs: mouse
Gene size: 12290bp
Exon count: 4