Full name: tripartite motif containing 24

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; hTIF1

Summary: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in testis (RPKM 19.9), ovary (RPKM 16.3) and 25 other tissues

Gene size: 129738bp

Exon count: 20