SUCLG1 succinate-CoA ligase GDP/ADP-forming subunit alpha [ Homo sapiens (human) ] - Gene - Data resources

8802

SUCLG1 succinate-CoA ligase GDP/ADP-forming subunit alpha [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8802)

Symbol: SUCLG1

Full name: succinate-CoA ligase GDP/ADP-forming subunit alpha

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GALPHA; MTDPS9; SUCLA1

Summary: This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]

Expression: Broad expression in kidney (RPKM 188.3), duodenum (RPKM 98.6) and 25 other tissues

Orthologs: mouse

Gene size: 35753bp

Exon count: 9