Full name: TNF receptor superfamily member 6b

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DCR3; DJ583P15.1.1; M68; M68E; TR6

Summary: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]

Expression: Broad expression in appendix (RPKM 7.2), spleen (RPKM 3.2) and 20 other tissues

Gene size: 2033bp

Exon count: 3