TNFRSF14 TNF receptor superfamily member 14 [ Homo sapiens (human) ] - Gene - Data resources

8764

TNFRSF14 TNF receptor superfamily member 14 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8764)

Symbol: TNFRSF14

Full name: TNF receptor superfamily member 14

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ATAR; CD270; HVEA; HVEM; LIGHTR; TR2

Summary: This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Expression: Ubiquitous expression in spleen (RPKM 22.9), duodenum (RPKM 21.7) and 23 other tissues

Orthologs: mouse

Gene size: 9596bp

Exon count: 12