SLC4A4 solute carrier family 4 member 4 [ Homo sapiens (human) ] - Gene - Data resources

8671

SLC4A4 solute carrier family 4 member 4 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8671)

Symbol: SLC4A4

Full name: solute carrier family 4 member 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HNBC1; KNBC; NBC1; NBC2; NBCe1; NBCe1-A; SLC4A5; hhNMC; kNBC1; pNBC

Summary: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Expression: Biased expression in kidney (RPKM 56.0), pancreas (RPKM 31.5) and 12 other tissues

Orthologs: mouse

Gene size: 509424bp

Exon count: 37