CADPS calcium dependent secretion activator [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8618)
Source: NCBI Gene (ID 8618)
Symbol: CADPS
Full name: calcium dependent secretion activator
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CADPS1; CAPS; CAPS1; UNC-31
Summary: This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
Expression: Biased expression in brain (RPKM 14.7), adrenal (RPKM 5.4) and 9 other tissues
Orthologs: mouse
Gene size: 477069bp
Exon count: 36