Full name: regulator of G protein signaling 20

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: RGSZ1; ZGAP1; g(z)GAP; gz-GAP

Summary: The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Expression: Biased expression in brain (RPKM 2.5), thyroid (RPKM 0.6) and 3 other tissues

Gene size: 107510bp

Exon count: 8