PIR pirin [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8544)
Source: NCBI Gene (ID 8544)
Symbol: PIR
Full name: pirin
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Summary: This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in fat (RPKM 9.0), urinary bladder (RPKM 8.0) and 24 other tissues
Orthologs: mouse
Gene size: 108535bp
Exon count: 10