Full name: zinc finger CCHC-type and RNA binding motif containing 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MADP-1; MADP1; RBM36; SNRNP31; ZCCHC19

Summary: Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in testis (RPKM 32.6), brain (RPKM 19.2) and 25 other tissues

Gene size: 14009bp

Exon count: 8