LINGO1 leucine rich repeat and Ig domain containing 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 84894)
Symbol: LINGO1
Full name: leucine rich repeat and Ig domain containing 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: LERN1; LRRN6A; MRT64; UNQ201
Summary: Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within generation of neurons and protein kinase B signaling. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. Implicated in autosomal recessive non-syndromic intellectual disability and glaucoma. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in brain (RPKM 24.2), placenta (RPKM 1.9) and 3 other tissues
Orthologs: mouse
Gene size: 207874bp
Exon count: 17