NSMAF neutral sphingomyelinase activation associated factor [ Homo sapiens (human) ] - Gene - Data resources

8439

NSMAF neutral sphingomyelinase activation associated factor [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8439)

Symbol: NSMAF

Full name: neutral sphingomyelinase activation associated factor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FAN; GRAMD5

Summary: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

Expression: Ubiquitous expression in lymph node (RPKM 12.0), appendix (RPKM 10.7) and 25 other tissues

Orthologs: mouse

Gene size: 76350bp

Exon count: 33