Full name: capping actin protein, gelsolin like

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AFCP; HEL-S-66; MCP

Summary: This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

Expression: Broad expression in lung (RPKM 44.7), esophagus (RPKM 37.5) and 22 other tissues

Gene size: 27939bp

Exon count: 17