Full name: mediator complex subunit 25

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ACID1; ARC92; BVSYS; CMT2B2; P78; PTOV2; TCBAP0758

Summary: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]

Expression: Broad expression in testis (RPKM 24.2), adrenal (RPKM 11.6) and 25 other tissues

Gene size: 22096bp

Exon count: 19