Full name: dual specificity phosphatase 16

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MKP-7; MKP7

Summary: This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010]

Expression: Ubiquitous expression in adrenal (RPKM 19.6), liver (RPKM 13.0) and 25 other tissues

Gene size: 89582bp

Exon count: 10