Full name: sarcospan

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DAGA5; KRAG; NSPN; SPN1; SPN2

Summary: This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Expression: Ubiquitous expression in heart (RPKM 16.0), ovary (RPKM 15.7) and 22 other tissues

Gene size: 112787bp

Exon count: 7