Full name: SHOC2 leucine rich repeat scaffold protein

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NSLH1; SIAA0862; SOC2; SUR8

Summary: This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010]

Expression: Ubiquitous expression in testis (RPKM 10.0), bone marrow (RPKM 7.4) and 25 other tissues

Gene size: 94296bp

Exon count: 11