Full name: potassium voltage-gated channel interacting protein 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CALP; KCHIP4

Summary: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Expression: Broad expression in brain (RPKM 3.7), endometrium (RPKM 1.2) and 15 other tissues

Gene size: 1220167bp

Exon count: 14