Full name: platelet derived growth factor D

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: IEGF; MSTP036; SCDGF-B; SCDGFB

Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]

Expression: Biased expression in adrenal (RPKM 66.8), ovary (RPKM 41.5) and 13 other tissues

Gene size: 256959bp

Exon count: 7