Full name: calmodulin 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; PHKD1; caM

Summary: This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.[provided by RefSeq, May 2020]

Expression: Ubiquitous expression in brain (RPKM 439.8), esophagus (RPKM 93.6) and 24 other tissues

Gene size: 11767bp

Exon count: 8