Full name: RecQ protein-like 4

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: RecQ4

Summary: Predicted to enable DNA binding activity and DNA helicase activity. Acts upstream of or within several processes, including negative regulation of sister chromatid cohesion; positive regulation of cell population proliferation; and skeletal system morphogenesis. Predicted to be located in chromosome, telomeric region. Predicted to be active in chromosome; cytoplasm; and nucleus. Is expressed in several structures, including Harderian gland; alimentary system; immune system; male reproductive gland or organ; and nervous system. Used to study Rothmund-Thomson syndrome. Human ortholog(s) of this gene implicated in Baller-Gerold syndrome; Rothmund-Thomson syndrome; and rapadilino syndrome. Orthologous to human RECQL4 (RecQ like helicase 4). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver E14.5 (RPKM 9.5), liver E14 (RPKM 8.4) and 28 other tissues

Gene size: 7068bp

Exon count: 22