Full name: WD repeat domain 77

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50

Summary: The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Expression: Ubiquitous expression in lymph node (RPKM 14.0), urinary bladder (RPKM 11.8) and 25 other tissues

Gene size: 9367bp

Exon count: 10