Nt5c2 5'-nucleotidase, cytosolic II [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 76952)
Source: NCBI Gene (ID 76952)
Symbol: Nt5c2
Full name: 5'-nucleotidase, cytosolic II
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2010002I23Rik; CnII; Gm9751; Gmp; Nt5b; Pnt5; cN-II
Summary: Enables GMP 5'-nucleotidase activity. Involved in GMP catabolic process to guanine; allantoin metabolic process; and dGMP catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in whole brain E14.5 (RPKM 17.2), CNS E14 (RPKM 14.7) and 28 other tissues
Orthologs: human
Gene size: 129785bp
Exon count: 27