Full name: MFSD2 lysolipid transporter A, lysophospholipid

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1700018O18Rik; Mfsd2; NLS1

Summary: Enables fatty acid transmembrane transporter activity; lysophosphatidylcholine flippase activity; and lysophospholipid:sodium symporter activity. Involved in central nervous system development; lipid transport; and transcytosis. Acts upstream of or within several processes, including photoreceptor cell development; regulation of lipid metabolic process; and retina development in camera-type eye. Located in plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 15. Orthologous to human MFSD2A (major facilitator superfamily domain containing 2A). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in genital fat pad adult (RPKM 42.1), liver adult (RPKM 18.7) and 19 other tissues

Gene size: 15202bp

Exon count: 15