ZFP36 ZFP36 ring finger protein [ Homo sapiens (human) ]
Source: NCBI Gene (ID 7538)
Source: NCBI Gene (ID 7538)
Symbol: ZFP36
Full name: ZFP36 ring finger protein
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: G0S24; GOS24; NUP475; RNF162A; TIS11; TTP; zfp-36
Summary: Enables several functions, including 14-3-3 protein binding activity; heat shock protein binding activity; and mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and regulation of gene expression. Acts upstream of or within mRNA catabolic process. Located in cytoplasmic ribonucleoprotein granule; cytosol; and nucleus. Part of ribonucleoprotein complex. Colocalizes with RISC-loading complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in gall bladder (RPKM 274.6), bone marrow (RPKM 248.5) and 25 other tissues
Orthologs: mouse
Gene size: 2561bp
Exon count: 2